Congratulations to Dr. Lorna Flanaghan on winning a poster prize at the The Irish Association for Cancer Research 2015 meeting

INHIBITION OF CASPASE-3 AS A NEW THERAPEUTIC APPROACH IN
COLON CANCER

L.Flanagan, S.Curry, M. Meyer, J. Fay, O. Bacon, E.W. Kay, D.A. McNamara, and J.H.M. Prehn

‘’We examined the role of executioner caspases in tissue regeneration following chemotherapy.Exploiting and antagonising this paracrine role of executioner caspases may be an interesting, novel approach for the treatment of tumours characterised by
resistance and relapse. Our data highlight that inhibition of Caspase-3, or
antagonising downstream effectors of Caspase-3 paracrine signalling, may
represent a novel approach to halt, or at least impede, tumour cell repopulation
following chemotherapy’

 

 

 

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