Monthly Archives: February 2015

A systems biological analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation.

The protease caspase-9 is activated on the apoptosome, a multi-protein signal transduction platform that assembles in response to mitochondria-dependent apoptosis initiation. Despite extensive molecular research, the assembly of the holo-apoptosome and the process of caspase-9 activation remain incompletely understood. Here … Continue reading

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“Abeta oligomers and brain inflammation link synapse failure to neuronal insulin resistance and depression in Alzheimer’s disease”

The Centre for Systems Medicine is delighted to announce another speaker to its 2015 seminar series:    Prof. Sergio T. Ferreira. Professor of Biophysics,Biochemistry, and Neuroscience, Institute of Biophysics Carlos Chagas Filho & Institute of Medical Biochemistry Leopoldo de Meis, Federal … Continue reading

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World Cancer Day Today, 4th February 2015

Cancer Research – Past, Present and Future. Leading Irish and International scientists discuss how cancer research and treatment has evolved in recent years, and what the future holds. https://www.youtube.com/watch?v=iSi2EO4zyQo&feature=youtu.be Systems Medicine symposium, BREAST-PREDICT,Irish Cancer Society Collaborative Cancer Research Centre marking … Continue reading

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