2022


Mechanisms and mathematical modelling of ROS production by the mitochondrial electron transport chain.
Chenna S, Koopman WJH, Prehn JHM, Connolly NMC.Am J Physiol Cell Physiol. 2022 May 25. doi: 10.1152/ajpcell.00455.2021. Online ahead of print.

 Serine-Arginine Protein Kinase 1 (SRPK1): a systematic review of its multimodal role in oncogenesis.Duggan WP, O’Connell E, Prehn JHM, Burke JP.Mol Cell Biochem. 2022 May 18. doi: 10.1007/s11010-022-04456-7. Online ahead of print.PMID: 35583632 Review.

Modelling α-Synuclein Aggregation and Neurodegeneration with Fibril Seeds in Primary Cultures of Mouse Dopaminergic Neurons.Tourville A, Akbar D, Corti O, Prehn JHM, Melki R, Hunot S, Michel PP.Cells. 2022 May 13;11(10):1640. doi: 10.3390/cells11101640.PMID: 35626675


An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution.
Lindner AU, Salvucci M, McDonough E, Cho S, Stachtea X, O’Connell EP, Corwin AD, Santamaria-Pang A, Carberry S, Fichtner M, Van Schaeybroeck S, Laurent-Puig P, Burke JP, McNamara DA, Lawler M, Sood A, Graf JF, Rehm M, Dunne PD, Longley DB, Ginty F, Prehn JHM.Cell Death Differ. 2022 Apr;29(4):806-817. doi: 10.1038/s41418-021-00895-9. Epub 2021 Nov 9.PMID: 34754079 Free PMC article.

 Share Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations.Stachtea X, Loughrey MB, Salvucci M, Lindner AU, Cho S, McDonough E, Sood A, Graf J, Santamaria-Pang A, Corwin A, Laurent-Puig P, Dasgupta S, Shia J, Owens JR, Abate S, Van Schaeybroeck S, Lawler M, Prehn JHM, Ginty F, Longley DB.Mod Pathol. 2022 Apr;35(4):564-576. doi: 10.1038/s41379-021-00953-0. Epub 2021 Nov 3.PMID: 34732839 Free PMC article.