Section 2 Selected Publications  

Name of Source Google Scholar
Hyperlink to Profile
Number of publications 290 Number of citations 17,053
H-index 69 Year of 1st publication 1991


  1. Quinlan S, Merino-Serrais P, Di Grande A, Dussmann H, Prehn JHM, Ní Chonghaile T, Henshall DC, Jimenez-Mateos EM. The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia. Front Immunol. 2019 Jul 24;10:1752. PMID:31396238 (IF 4.1)
  2. Crivello M, Hogg MC, Jirström E, Halang L, Woods I, Rayner M, Coughlan KS, Lewandowski SL, Prehn JHM. Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model. Dis Model Mech. 2019 Aug 13;12(8). PMID:31383794 (IF 4.0)
  3. Alves M, De Diego Garcia L, Conte G, Jimenez-Mateos EM, D’Orsi B, Sanz-Rodriguez A, Prehn JHM, Henshall DC, Engel T. Context-Specific Switch from Anti- to Pro-epileptogenic Function of the P2Y(1) Receptor in Experimental Epilepsy. J Neurosci. 2019 Jul 3;39(27):5377-5392. PMID 31048325 (IF 6.0)
  4. Hogg MC, Raoof R, El Naggar H, Monsefi N, Delanty N, O’Brien DF, Bauer S, Rosenow F, Henshall DC, Prehn JHM. Elevation in plasma tRNA fragments precede seizures in human epilepsy. J Clin Invest. 2019 Apr 30;129(7):2946-2951. PMID: 31039137 (IF 12.28)
  5. Theurey P, Connolly NMC, Fortunati I, Basso E, Lauwen S, Ferrante C, Moreira Pinho C, Joselin A, Gioran A, Bano D, Park DS, Ankarcrona M, Pizzo P, Prehn JHM. Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer’s disease neurons. Aging Cell. 2019 Jun;18(3):e12924. PMID: 30793475 (IF 7.6, C1)
  6. Raoof R, Bauer S, El Naggar H, Connolly NMC, Brennan GP, Brindley E, Hill T, McArdle H, Spain E, Forster RJ, Prehn JHM, Hamer H, Delanty N, Rosenow F, Mooney C, Henshall DC. Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy. EBioMedicine. 2018 Dec;38:127-141. doi: 10.1016/j.ebiom.2018.10.068. PMID: 30396857 (IF 6.6 C3)
  7. Kinsella S, Fichtner M, Watters O, König HG, Prehn JHM. Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation. J Neuroinflammation. 2018 May 2;15(1):130. PMID: 29720226 (IF 5.1 C1ba)
  8. Bano D, Prehn JHM. Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer. 2018 Apr;30:29-37. PMID 29605508 (IF 6.6)
  9. Crivello M, O’Riordan SL, Woods I, Cannon S, Halang L, Coughlan KS, Hogg MC, Lewandowski SA, Prehn JHM. Pleiotropic activity of systemically delivered angiogenin in the SOD1(G93A) mouse model. Neuropharmacology. 2018 May 1;133:503-511. PMID: 29486168 (IF 4.2)
  10. Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death Differ. 2018 Mar;25(3):542-572. PMID: 29229998 (IF 8.0 C8)
  11. Hogg MC, Halang L, Woods I, Coughlan KS, Prehn JHM. Riluzole does not improve lifespan or motor function in three ALS mouse models. Amyotroph Lateral Scler Frontotemporal Degener. 2018 Aug;19(5-6):438-445. PMID: 29221425 (IF 2.8 C1)
  12. Raoof R, Jimenez-Mateos EM, Bauer S, Tackenberg B, Rosenow F, Lang J, Onugoren MD, Hamer H, Huchtemann T, Körtvélyessy P, Connolly NMC, Pfeiffer S, Prehn JHM, Farrell MA, O’Brien DF, Henshall DC, Mooney C. Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus. Sci Rep. 2017 Jun 12;7(1):3328. PMID: 28607431 (IF 4.5)
  13. König HG, Schwamborn R, Andresen S, Kinsella S, Watters O, Fenner B, Prehn JHM. NF-κB regulates neuronal ankyrin-G via a negative feedback loop. Sci Rep. 2017 Feb 9;7:42006. PMID: 28181483 (IF 4.5)
  14. Henshall DC, Hamer HM, Pasterkamp RJ, Goldstein DB, Kjems J, Prehn JHM, Schorge S, Lamottke K, Rosenow F. MicroRNAs in epilepsy: pathophysiology and clinical utility. Lancet Neurol. 2016 Dec;15(13):1368-1376. PMID: 27839653 (IF 28 C35)
  15. Haunsberger SJ, Connolly NM, Prehn JHM. miRNAmeConverter: an R/Bioconductor package for translating mature miRNA names to different miRBase versions. 2017 Feb 15;33(4):592-593. PMID: 27797767 (IF 4.5)
  16. Coughlan KS, Halang L, Woods I, Prehn JHM. A high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP-43A315T mutant C57BL6/J mice. Dis Model Mech. 2016 Sep 1;9(9):1029-37. PMID 27491077 (IF 4.316)
  17. Kinsella S, König HG, Prehn JHM. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. eNeuro. 2016 May 12;3(2).
  18. D’Orsi B, Engel T, Pfeiffer S, Nandi S, Kaufmann T, Henshall DC, Prehn JH. Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. J Neurosci. 2016 Apr 20;36(16):4564-78. (IF: 6.344)
  19. Hogg MC, Mitchem MR, König HG, Prehn JH. Caspase 6 has a protective role in SOD1(G93A) transgenic mice. Biochim Biophys Acta. 2016 Jun;1862(6):1063-73 (IF: 3.66)
  20. O’Halloran PJ, Viel T, Murray DW, Wachsmuth L, Schwegmann K, Wagner S, Kopka K, Jarzabek MA, Dicker P, Hermann S, Faber C, Klasen T, Schäfers M, O’Brien D, Prehn JH, Jacobs AH, Byrne AT. Mechanistic interrogation of combination bevacizumab/dual PI3K/mTOR inhibitor response in glioblastoma implementing novel MR and PET imaging biomarkers. Eur J Nucl Med Mol Imaging. 2016 Aug;43(9):1673-83. (IF: 5.383)
  21. Connolly NM, D’Orsi B, Monsefi N, Huber HJ, Prehn JH. Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions. PLoS One. 2016 Feb 3;11(2):e0148326. (IF: 3.234)
  22. Walter F, Schmid J, Düssmann H, Concannon CG, Prehn JH. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival. Cell Death Differ. 2015 Sep;22(9):1502-16. (IF: 184; C:11)
  23. D’Orsi B, Kilbride SM, Chen G, Perez Alvarez S, Bonner HP, Pfeiffer S, Plesnila N, Engel T, Henshall DC, Düssmann H, Prehn JH. Bax regulates neuronal Ca2+ homeostasis. J Neurosci. 2015 Jan 28;35(4):1706-22. (IF:6.344)
  24. Connolly NM, Düssmann H, Anilkumar U, Huber HJ, Prehn JH. Single-cell imaging of bioenergetic responses to neuronal excitotoxicity and oxygen and glucose deprivation. J Neurosci. 2014 Jul 30;34(31):10192-205. (IF: 6.344; C:6)
  25. Concannon CG, Tuffy LP, Weisová P, Bonner HP, Dávila D, Bonner C, Devocelle MC, Strasser A, Ward MW, Prehn JH. AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. J Cell Biol. 2010 Apr 5;189(1):83-94. (IF:9.834; C: 81)
  26. Davila D, Connolly NM, Bonner H, Weisová P, Dussmann H, Concannon CG, Huber HJ, Prehn JH. Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate. Cell Death Differ. 2012 Oct;19(10):1677-88. (IF: 8.184; C:33)
  27. Skorupa A, King MA, Aparicio IM, Dussmann H, Coughlan K, Breen B, Kieran D, Concannon CG, Marin P, Prehn JH. Motoneurons secrete angiogenin to induce RNA cleavage in astroglia. J Neurosci. 2012 Apr 11;32(15):5024-38. (IF : 6.344 ; C:31)
  28. D’Orsi B, Bonner H, Tuffy LP, Düssmann H, Woods I, Courtney MJ, Ward MW, Prehn, JH. Calpains are downstream effectors of bax-dependent excitotoxic apoptosis. J Neurosci. 2012 Feb 1;32(5):1847-58. (IF: 6.344; C:39)
  29. Tuffy LP, Concannon CG, D’Orsi B, King MA, Woods I, Huber HJ, Ward MW, Prehn JH. Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. Mol Cell Biol. 2010 Dec;30(23):5484-501. (IF: 6.459; C:10)
  30. Kilbride SM, Farrelly AM, Bonner C, Ward MW, Nyhan KC, Concannon CG, Wollheim CB, Byrne MM, Prehn JH. AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF. J Biol Chem. 2010 November 12; 285(46): 36199–36206. (IF: 4.573; C:23)
  31. Engel T, Murphy BM, Hatazaki S, Jimenez-Mateos EM, Concannon CG, Woods I, Prehn JH, Henshall DC. Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. FASEB J. 2010 Mar;24(3):853-61. (IF:5.299; C: 46)
  32. Sebastià J, Kieran D, Breen B, King MA, Netteland DF, Joyce D, Fitzpatrick SF, Taylor CT, Prehn JH. Angiogenin protects motoneurons against hypoxic injury. Cell Death Differ. 2009 Sep;16(9):1238-47. (IF:8.184; C: 72)
  33. Weisová P, Concannon CG, Devocelle M, Prehn JH, Ward MW. Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. J Neurosci. 2009 Mar 4;29(9):2997-3008. (IF:6.344; C:87)
  34. Kieran D, Sebastia J, Greenway MJ, King MA, Connaughton D, Concannon CG, Fenner B, Hardiman O, Prehn JH. Control of motoneuron survival by angiogenin. J Neurosci. 2008 Dec 24;28(52):14056-61. (IF:6.344; C:114)
  35. Kieran D,Woods I, Villunger A, Strasser A, Prehn JH. Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice. Proc Natl Acad Sci USA. 2007 Dec18;104(51):20606 (IF: 9.423; C:110)
  36. Ward MW, Huber HJ, Weisová P, Düssmann H, Nicholls DG, Prehn JH. Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance. J Neurosci. 2007 Aug 1;27(31):8238-49. (IF: 6.344; C:89)
  37. Greenway MJ, Andersen PM, Russ C, Ennis S, Cashman S, Donaghy C, Patterson V, Swingler R, Kieran D, Prehn J, Morrison KE, Green A, Acharya KR, Brown RH Jr, Hardiman O. ANG mutations segregate with familial and ‘sporadic’ amyotrophic lateral sclerosis. Nat Genet. 2006 Apr;38(4):411-3. (IF:31.6; C: 514)