MEL-PLEX Worshop Wednesday 6th May 2015

Innovative Approaches in Translational Melanoma Research

MEL-PLEX is a Marie Skłodoswska-Curie
Innovative Training Network funded by Horizon 2020 aiming to train a new
generation of researchers that can navigate confidently between clinical,
academic and private sector environments. As part of its training programme,
MEL-PLEX will hold a training course which will consist of workshop to provide
an overview of the current status of malignant melanoma management and the
field of translational cancer systems biology and systems medicine, followed by
a Transferable Skills course to introduce the new PhD students to basic topics
in scientific research.

The main topics addressed
include:

  • Melanoma
    pathology and treatment
  • Melanoma
    proliferation and migration
  • Kinase
    cascades in melanoma
  • Cell
    death modalities in melanoma
  • Biomarker
    identification and validation
  • Targeted
    drugs and drug development
  • Innovative
    experimental models
  • Applied
    Systems Biology
  • Systems
    Medicine strategies

The workshop entitled “Innovative
Approaches in Translational Melanoma Research” is an open event. Deadline for
registration is April 24th 2015.

For more information and free
registration please contact: melplexETN@rcsi.ie

Venue: Cheyne Lecture Theatre, RCSI, 9am
Wednesday 6th May 2015

Seminar: “Systems pharmacology and pharmacokinetic/pharmacodynamic modelling Oncology”

The Centre for
Systems Medicine is delighted to announce
distinguished  speakers to its 2015 seminar series:
 


Prof. Donald Mager
, Associate Professor of Pharmaceutical Sciences at the University at Buffalo, State University of New York (UB) 
Bio: –http://pharmsci.buffalo.edu/CEPKPD/faculty/MAGER.HTML

and

Prof.Robert Straubinger, Professor of Pharmaceutical
Sciences
at University at Buffalo School of Pharmacy.

Bio: –http://pharmsci.buffalo.edu/CEPKPD/faculty/STRB.HTML

Venue:
Houston Lecture Theatre, RCSI, 4.30 Pm Tuesday 10th March 2015

 

Congratulations to Dr. Lorna Flanaghan on winning a poster prize at the The Irish Association for Cancer Research 2015 meeting

INHIBITION OF CASPASE-3 AS A NEW THERAPEUTIC APPROACH IN
COLON CANCER

L.Flanagan, S.Curry, M. Meyer, J. Fay, O. Bacon, E.W. Kay, D.A. McNamara, and J.H.M. Prehn

‘’We examined the role of executioner caspases in tissue regeneration following chemotherapy.Exploiting and antagonising this paracrine role of executioner caspases may be an interesting, novel approach for the treatment of tumours characterised by
resistance and relapse. Our data highlight that inhibition of Caspase-3, or
antagonising downstream effectors of Caspase-3 paracrine signalling, may
represent a novel approach to halt, or at least impede, tumour cell repopulation
following chemotherapy’