Dr. Shona Pfeiffer is a senior researcher in the Department of Physiology & Medical Physics. She received her B.Sc (Hons) degree in Biochemistry in 2007 from University College Dublin (UCD) and subsequently was awarded a Ph.D. in Neuroscience in 2011, focusing on the development of novel neuronal differentiation protocols for human amniotic fluid-derived stem cells as a therapeutically relevant stem cell source in the treatment of neurodegenerative diseases. She continued her interest in translational neuroscience and novel therapies in the treatment of neurological disorders as a post-doctoral researcher in the Centre for Systems Medicine, RCSI, in the laboratory of Prof. Jochen Prehn. Her research has focused on cell death mechanisms and their implication for human disease, with particular focus on AMPK signalling and Bcl-2 family proteins in acute ischaemic neuronal injury, as well as involvement in translational research projects identifying circulating biomarkers and new target structures for the treatment of diabetes mellitus and cancer. She was appointed assistant lecturer in the Department of Physiology & Medical Physics in 2014 and awarded a Postgraduate Diploma in Health Professions Education in 2016.
Dr. Pfeiffer focuses on translational collaborative research in clinically relevant settings for the development of diagnostic, prognostic and novel protective agents in clinical intervention for neuroprotection in ischaemic stroke and in the treatment of diabetes mellitus. Her main research interests are AMPK signalling and gene regulation during energetic stress as biomarkers and therapeutic targets in the treatment of neuronal injury, diabetes mellitus and cancer. Click for her research interests