2013 – 2012 – 2011 – 2010 – 2009 – 2008 – 2007 – 2006 – 2005 – 2003 – and earlier

2013:

• Bonner C, Nyhan KC, Bacon S, Kyithar MP, Schmid J, Concannon CG, Bray IM, Stallings RL, Prehn JH, Byrne MM. Identification of circulating microRNAs in HNF1A-MODY carriers. Diabetologia. 2013 May 15. PMID: 23674172
• Rehm M, Prehn JH. Systems modelling methodology for the analysis of apoptosis signal transduction and cell death decisions. Methods. 2013 Apr 19. PMID: 23607991
• Jarzabek MA, Huszthy PC, Skaftnesmo KO, McCormack E, Dicker P, Prehn JH, Bjerkvig R, Byrne AT. In Vivo Bioluminescence Imaging Validation of a Human Biopsy-derived Orthotopic Mouse Model of Glioblastoma Multiforme. Mol Imaging. 2013 Mar 1;12(2):1-12. PMID: 23422278
• Engel T, Sanz-Rodgriguez A, Jimenez-Mateos EM, Concannon CG, Jimenez-Pacheco A, Moran C, Mesuret G, Petit E, Delanty N, Farrell MA, O’Brien DF, Prehn JH, Lucas JJ, Henshall DC. CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures. Brain. 2013 Jan 29. PMID: 23361066
• Lindner AU, Concannon CG, Boukes GJ, Cannon MD, Llambi F, Ryan D, Boland K, Kehoe J, McNamara DA, Murray F, Kay EW, Hector S, Green DR, Huber HJ, Prehn JH. Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy. Cancer Res. 2013 Jan 15;73(2):519-28. doi: 10.1158/0008-5472.CAN-12-2269. PMID: 23329644
• Behan AT, Breen B, Hogg M, Woods I, Coughlan K, Mitchem M, Prehn JH. Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration. Cell Death Differ. 2013 Jan 11. doi: 10.1038/cdd.2012.158. PMID: 23306556

2012:

• Anilkumar U, Weisová P, Düssmann H, Concannon CG, König HG, Prehn JH. AMP-activated Protein Kinase (AMPK)-Induced Preconditioning in Primary Cortical Neurons Involves Activation of MCL-1. J Neurochem. 2012 Nov 30. doi: 10.1111/jnc.12108. PMID: 23199202
• Aparicio-Erriu IM, Prehn JH. Molecular Mechanisms in Amyotrophic Lateral Sclerosis: The Role of Angiogenin, a Secreted RNase. Front Neurosci. 2012;6:167. doi: 10.3389/fnins.2012.00167. Epub 2012 Nov 19. PMID: 23181008
• König HG, Fenner BJ, Byrne JC, Schwamborn RF, Bernas T, Jefferies CA, Prehn JH. Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-κB signaling in neurons. J Cell Sci. 2012 Oct 24. PMID: 23097049
• Weyhenmeyer B, Murphy AC, Prehn JH, Murphy BM. Targeting the anti-apoptotic bcl-2 family members for the treatment of cancer. Exp Oncol. 2012 Oct;34(3):192-9. PubMed PMID: 23070004.
• Schmid J, Dussmann H, Boukes GJ, Flanagan L, Lindner AU, O’Connor CL, Rehm M, Prehn JH, Huber HJ. Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilisation. J Biol Chem. 2012 Oct 4. [Epub ahead of print] PMID: 23038270
• Farrell MP, Hughes DJ, Berry IR, Gallagher DJ, Glogowski EA, Payne SJ, Kennedy MJ, Clarke RM, White SA, Muldoon CB, Macdonald F, Rehal P, Crompton D, Roring S, Duke ST, McDevitt T, Barton DE, Hodgson SV, Green AJ, Daly PA. Clinical correlation and molecular evaluation confirm that the MLH1 p.Arg182Gly (c.544A/G) mutation is pathogenic and causes Lynch syndrome. Familial Cancer. 2012 Jul 7. [Epub ahead of print]PMID: 22773173
• Kilbride SM, Prehn JH. Central roles of apoptotic proteins in mitochondrial function. Oncogene. 2012 Aug 6. doi: 10.1038/onc.2012.348. [Epub ahead of print] PubMed PMID: 22869150.
• Bacon S, Kyithar MP, Schmid J, Rizvi SR, Bonner C, Graf R, Prehn JH, Byrne MM. Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1
  alpha (HNF1A-MODY) carriers from the third decade of life onward. BMC Endocr Disord. 2012 Jul 18;12:13. doi: 10.1186/1472-6823-12-13. PubMed PMID: 22808921; PubMed Central PMCID: PMC3433346.
• Ionescu CM, Svobodova-Varekova R, Prehn JHM, Huber HJ, Koca J, Charge Profile Analysis Reveals That Activation of Pro-apoptotic Regulators Bax and Bak Relies on Charge Transfer Mediated Allosteric Regulation, Plos Comp. Biol., doi:10.1371/journal.pcbi.1002565
• Weisová P, Anilkumar U, Ryan C, Concannon CG, Prehn JH, Ward MW. ‘Mild
  mitochondrial uncoupling’ induced protection against neuronal excitotoxicity
  requires AMPK activity. Biochim Biophys Acta. 2012 May;1817(5):744-53. Epub 2012
  Feb 7. PubMed PMID: 22336583.
• Davila D, Connolly NM, Bonner H, Weisova P, Dussmann H, Concannon C, Huber HJ, Prehn J, Two step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate, Cell Death Diff. 2012 Apr 27. doi: 10.1038/cdd.2012.49. [Epub ahead of print] PMID:22539004
• Hector S, Conlon S, Schmid J, Dicker P, Cummins RJ, Concannon CG, Johnston PG, Kay EW, Prehn JH. Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer., Br J Cancer. 2012 Apr 24;106(9):1499-1505. doi: 10.1038/bjc.2012.133
• Skorupa A, King MA, Aparicio IM, Dussmann H, Coughlan K, Breen B, Kieran D,
  Concannon CG, Marin P, Prehn JH. Motoneurons secrete angiogenin to induce RNA
  cleavage in astroglia. J Neurosci. 2012 Apr 11;32(15):5024-38. PubMed PMID:
  22496549.
• Laussmann MA, Passante E, Hellwig CT, Tomiczek B, Flanagan L, Prehn JH, Huber HJ, Rehm M. Proteasome inhibition can impair caspase-8 Activation upon sub-maximal Stimulation of apoptotic tumour necrosis factor-related apoptosis inducing ligand (TRAIL) signalling. J Biol Chem, 2012 Mar 9; [Epub ahead of print]. PMID 22408249
• Sehnal D, Svobodova-Varekova R, Huber HJ, Geidl S, Ionescu CM, Wimmerova M, Koca J, SiteBinder – an improved approach for comparing multiple protein structural motifs, J. Chem. Inf. Model. 2012 (PMID 22296449)
• Huber HJ, Connolly NM, Dussmann H, Prehn JHM,  A structured approach to the study of metabolic control principles in intact and impaired mitochondria, Molecular Biosystems, 2012 Mar;8(3):828-42.
• D’Orsi B, Bonner H, Tuffy LP, Düssmann H, Woods I, Courtney MJ, Ward MW, Prehn JH. Calpains are downstream effectors of bax-dependent excitotoxic apoptosis. J Neurosci. 2012 Feb 1;32(5):1847-58. PubMed PMID: 22302823.
• Hector S, Chen H, Kijanka G, Murray F, Prehn JH. A reverse-ELISA for the
  detection of TRIM28/KAP1 serum autoantibodies in colorectal cancer patients. Acta
  Oncol. 2012 Mar;51(3):394-6. Epub 2012 Jan 24. PubMed PMID: 22268577.
• Lopez-Caamal F, Garcia M, Middleton RH, Huber HJ, Positive Feedback in the AKT/mTOR pathway and its implications for growth signal progression in skeletal muscle cells, J. Theor. Biol. 2012 Feb 2;301C:15-27.
• Würstle ML, Laussmann MA, Rehm M. The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome. Exp Cell Res 2012 (Special Issue on Cell Death Signalling) in press. PMID: 22406265
• Hellwig CT, Rehm M. TRAIL signalling and synergy mechanisms used in TRAIL-based combination therapies. Mol Cancer Ther. 2012 Jan;11(1):3-13. PMID: 22234808.
• Ebert MP, Tänzer M, Balluff B, Burgermeister E, Kretzschmar AK, Hughes DJ,
  Tetzner R, Lofton-Day C, Rosenberg R, Reinacher-Schick AC, Schulmann K, Tannapfel A, Hofheinz R, Röcken C, Keller G, Langer R, Specht K, Porschen R,
  Stöhlmacher-Williams J, Schuster T, Ströbel P, Schmid RM. TFAP2E-DKK4 and
  Chemoresistance in Colorectal Cancer. N Engl J Med. 2012 Jan 5;366(1):44-53.
  PubMed PMID: 22216841.

2011:

• Hector S, Rehm M, Schmid J, Kehoe J, McCawley N, Dicker P, Murray F, McNamara D, Kay EW, Concannon CG, Huber HJ, Prehn JH. Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy. Gut. 2011 Nov 14. [Epub ahead of print] PMID: 22082587
• McCawley N, Conlon S, Hector S, Cummins RJ, Dicker P, Johnston PG, Kay EW, McNamara DA, Prehn JH, Concannon CG. Analyzing proteasomal subunit expression reveals Rpt4 as a prognostic marker in stage II colorectal cancer. Int J Cancer. 2011 Sep 29. doi: 10.1002/ijc.26468. PMID: 21960357
  Farrelly AM, Kilbride SM, Bonner C, Prehn JH, Byrne MM. Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells. Apoptosis. 2011 Nov;16(11):1128-37.PMID: 21874357
• Vader P, van der Meel R, Symons M H, Fens M H A M, Pieters E, Wilschut K J, Storm G, Jarzabek M, Gallagher W, Schiffelers R M, Byrne A T Examining the role of Rac1 in tumor angiogenesis and growth: a clinically relevant RNAi-mediated approach. Angiogenesis. 2011 Dec;14(4):457-66. Epub 2011 Jul 26. PMID: 21789714
• Kedziora KM, Prehn JH, Dobrucki J, Bernas T. Method of calibration of a fluorescence microscope for quantitative studies. J Microsc. 2011 Oct;244(1):101-11. doi: 10.1111/j.1365-2818.2011.03514.x. Epub 2011 Jul 14. PMID: 21756257
• Bonner C, Farrelly AM, Concannon CG, Dussmann H, Baquié M, Virard I, Wobser H, Kögel D, Wollheim CB, Rupnik M, Byrne MM, König HG, Prehn JH. Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation.  J Biol Chem. 2011 Jul 22;286(29):25719-28. Epub 2011 May 31. PMID: 21628466
• Hams E, Saunders SP, Cummins EP, O’Connor A, Tambuwala MT, Gallagher WM, Byrne AT, Campos-Torres A, Moynagh PM, Jobin C, Taylor CT, Fallon PG. The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells. Shock. 2011 Sep;36(3):295-302. PMID: 21844787
• Huber HJ, Dussmann H, Kilbride SM, Rehm M, Prehn JH. Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release. Mol Syst Biol. 2011 Mar 1;7:470. PMID: 21364572
• Laussmann MA, Passante E, Dussmann H, Rauen JA, Würstle ML, Delgado ME, Devocelle M, Prehn JH, Rehm M . Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8.Cell Death Differ. PMID: 21455219
• O’Connor AE, McGee MM, Likar Y, Ponomarev V, Callanan JJ, O’shea DF, Byrne AT, Gallagher WM . Mechanism of cell death mediated by a BF(2) -chelated tetraaryl-azadipyrromethene photodynamic therapeutic: Dissection of the apoptotic pathway in vitro and in vivo. International Journal of Cancer 2011 Mar 16. doi: 10.1002/ijc.26073. PMID: 21413012
• Engel T, Plesnila N, Prehn JH, Henshall DC. In vivo contributions of BH3-only
  proteins to neuronal death following seizures, ischemia, and traumatic brain
  injury. J Cereb Blood Flow Metab. 2011 May;31(5):1196-210. Epub 2011 Mar 2.
  Review. PubMed PMID: 21364604; PubMed Central PMCID: PMC3099642.
• Van der Meel R, Symons MH, Kudernatsch R, Kok RJ, Schiffelers RM, Storm G, Gallagher WM, Byrne AT.The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy. Drug Discov Today, 2011 Mar;16(5-6):219-28. Epub 2011 Jan 22.PMID: 21262381
• Huber HJ, Dussmann H, Kilbride SM, Rehm M, Prehn JH. AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF. Mol Syst Biol. 2011 Mar 1;7:470. PMID: 21364572
• Flanagan L, Sebastia J, Delgado ME, Lennon JC, Rehm M. Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization. Biochim Biophys Acta. 2011 Feb 23. [Epub ahead of print] PMID: 21354220
• Tummala R, Diegelman P, Hector S, Kramer DL, Clark K, Zagst P, Fetterly G, Porter CW, Pendyala L. Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants. Cancer Chemother Pharmacol. 2011 Feb;67(2):401-14. Epub 2010 May 5. PMID:20443003
• Tsuchiya T, Bonner HP, Engel T, Woods I, Matsushima S, Ward MW, Taki W,
  Henshall DC, Concannon CG, Prehn JH. Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome
  inhibition in vivo. Eur J Neurosci. 2011 Feb;33(3):401-8. doi: 10.1111/j.1460-9568.2010.07538.x. Epub 2010 Dec 31. PubMed PMID: 21198986.
• Hellwig CT, Passante E, Rehm M.The molecular machinery regulating apoptosis signal transduction and its implication in human physiology and pathophysiologies. Curr Mol Med. 2011 Feb;11(1):31-47. Review. PMID: 21189119

2010:

• Ludwig-Galezowska AH, Flanagan L, Rehm M . Apoptosis repressor with caspase recruitment domain, a multifunctional modulator of cell death. J Cell Mol Med. 2010 Dec 3. [Epub ahead of print] PMID: 21129150
• Bonner C, Bacon S, Concannon CG, Rizvi SR, Baquié M, Farrelly AM, Kilbride SM, Dussmann H, Ward MW, Boulanger CM, Wollheim CB, Graf R, Byrne MM, Prehn JH.INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells. Diabetes. 2010 Nov;59(11):2799-808. Epub 2010 Aug 3. PMID: 20682686
• Flanagan L, Sebastià J, Tuffy LP, Spring A, Lichawska A, Devocelle M, Prehn JH, Rehm M. XIAP impairs Smac release from the mitochondria during apoptosis. Cell Death Dis. 2010 Jun 3;1(6):e49. PMID: 21364655
• Huber HJ, Duessmann H, Wenus J, Kilbride SM, Prehn JH Mathematical modelling of the mitochondrial apoptosis pathway. Biochim Biophys Acta. 2011 Apr;1813(4):608-15. Epub 2010 Oct 13.
• Fitzpatrick SF, Tambuwala MM, Bruning U, Schaible B, Scholz CC, Byrne A, O’Connor A, Gallagher WM, Lenihan CR, Garvey JF, Howell K, Fallon PG, Cummins EP, Taylor CT . An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia.J Immunol. 2011 Jan 15;186(2):1091-6. PMID: 21149600.
• Kilbride SM, Farrelly AM, Bonner C, Ward MW, Nyhan KC, Concannon CG, Wollheim CB, Byrne MM, Prehn JH . AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF.J Biol Chem. 2010 Nov 12;285(46):36199-206. Epub 2010 Sep 14.PMID:20841353
• Concannon CG, Tuffy LP, Weisová P, Bonner HP, Dávila D, Bonner C, Devocelle
  MC, Strasser A, Ward MW, Prehn JH. AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. J Cell Biol. 2010 Apr 5;189(1):83-94. Epub 2010 Mar 29. PubMed PMID: 20351066; PubMed Central PMCID: PMC2854380.
• Würstle ML, Laussmann MA, Rehm M . The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling. J Biol Chem. 2010 Aug 11. PMID: 20702410
• Hellwig CT, Ludwig-Galezowska AH, Concannon CG, Litchfield DW, Prehn JH, Rehm M. Activity of protein kinase CK2 uncouples Bid cleavage from caspase-8 activation.. J Cell Sci. 2010 May 1;123(Pt 9):1401-6. Epub 2010 Mar 31. PMID: 20356928
• Strathmann J, Klimo K, Sauer SW, Okun JG, Prehn JH, Gerhäuser C. Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism.. FASEB J. 2010 Aug;24(8):2938-50. Epub 2010 Mar 24. PMID: 20335224
• Paul P, Duessmann H, Bernas T, Huber H, Kalamatianos D. Automatic noise quantification for confocal fluorescence microscopy images. Comput Med Imaging Graph. 2010 Sep;34(6):426-34. Epub 2010 May 13. PMID: 20462738
• O’Donovan N, Byrne A, O’Connor AE, McGee S, Gallagher WM, Crown J. Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells. Invest New Drugs. 2011 Oct;29(5):752-9. Epub 2010 Mar 16. PMID: 20229355
• O’Neill K, Lyons SK, Gallagher WM, Curran KM, Byrne AT Bioluminescent imaging: a critical tool in pre-clinical oncology research. J Pathol 2010 Feb;220(3):317-27 PMID: 19967724
• Fens MH, Storm G, Pelgrim RC, Ultree A, Byrne AT, Gaillard CA, van Solinge WW, Schiffelers RM . Erythrophagocytosis by angiogenic endothelial cells is enhanced by loss of erythrocyte deformability. Exp Hematol. 2010 Apr;38(4):282-91. Epub 2010 Feb 8. PMID: 20146933
• Huber HJ, Laussmann MA, Prehn JH, Rehm M. Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell death. BMC Syst Biol. 2010 Feb 4;4:9. PMID: 20132548
• Dervan EW, Chen H, Ho SL, Brummel N, Schmid J, Toomey D, Haralambova M, Gould E, Wallace DM, Prehn JH, O’Brien CJ, Murphy D. Protein macroarray profiling of serum autoantibodies in pseudoexfoliation glaucoma.. Invest Ophthalmol Vis Sci. 2010 Jun;51(6):2968-75. Epub 2010 Jan 27. PMID: 20107165
• Fenner BJ, Scannell M, Prehn JH. Expanding the substantial interactome of NEMO using protein microarrays. PLoS One. 2010 Jan 20;5(1):e8799. PMID: 20098747
• Kijanka G, Hector S, Kay EW, Murray F, Cummins R, Murphy D, MacCraith BD, Prehn JH, Kenny D. Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer.. Gut. 2010 Jan;59(1):69-78. Epub . PMID: 19828471

2009:

• Wenus J, Dussmann H, Paul P, Kalamatianos D, Rehm M, Wellstead P, Prehn JH, Huber HJ . ALISSA: an automated live-cell imaging system for signal transduction analyses. Biotechniques. 2009 Dec;47(6):1033-40 PMID: 20041856
• Byrne AT, O’Connor AE, Hall M, Murtagh J, O’Neill K, Curran KM, Mangrain K, Rousseau JA, Lecomte R, McGee S, Callanan JJ, O’Shea DF, Gallagher WM . Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: a multi-modality molecular imaging approach to therapeutic assessment. Br J Cancer. 2009 Nov 3;101(9):1565-73. Epub 2009 Oct 13.    PMID: 19826417
• Düssmann H, Rehm M, Concannon CG, Anguissola S, Würstle M, Kacmar S, Völler P, Huber HJ, Prehn JH. Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation. Cell Death Differ. 2010 Feb;17(2):278-90. Epub 2009 Sep 11. PMID:19745831
• O’Connor AE, Gallagher WM, Byrne AT . Porphyrin and nonporphyrin photosensitizers in oncology: preclinical and clinical advances in photodynamic therapy.  Photochem Photobiol. 2009 Sep-Oct;85(5):1053-74. Epub 2009 Aug 3PMID: 19682322
• Anguissola S, Köhler B, O’Byrne R, DüsSMann H, Cannon MD, Murray FE, Concannon CG, Rehm M, Kögel D, Prehn JH.  Bid and calpains cooperate to trigger oxaliplatin-induced apoptosis of cervical carcinoma HeLa cells. Mol Pharmacol. 2009 Nov;76(5):998-1010. Epub 2009 Aug 27. PMID: 19713356
• Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, Cohen GM, De Laurenzi V, De Maria R, Deshmukh M, Dynlacht BD, El-Deiry WS, Flavell RA, Fulda S, Garrido C, Golstein P, Gougeon ML, Green DR, Gronemeyer H, Hajnóczky G, Hardwick JM, Hengartner MO, Ichijo H, Jäättelä M, Kepp O, Kimchi A, Klionsky DJ, Knight RA, Kornbluth S, Kumar S, Levine B, Lipton SA, Lugli E, Madeo F, Malomi W, Marine JC, Martin SJ, Medema JP, Mehlen P, Melino G, Moll UM, Morselli E, Nagata S, Nicholson DW, Nicotera P, Nuñez G, Oren M, Penninger J, Pervaiz S, Peter ME, Piacentini M, Prehn JH, Puthalakath H, Rabinovich GA, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Scorrano L, Simon HU, Steller H, Tschopp J, Tsujimoto Y, Vandenabeele P, Vitale I, Vousden KH, Youle RJ, Yuan J, Zhivotovsky B, Kroemer G. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ. 2009 Aug;16(8):1093-107. Epub 2009 Apr 17. Review. PMID:19373242
• Fenner BJ, Scannell M, Prehn JH. Identification of polyubiquitin binding proteins involved in NF-kappaB signaling using protein arrays. Biochim Biophys Acta. 2009 Jul;1794(7):1010-6. Epub 2009 Mar 11. PMID: 19285159
• Hector S, Prehn JH. Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer: a review. Biochim Biophys Acta. 2009 Apr;1795(2):117-29. Epub 2009 Jan 6. Review. PMID:19167459
• Rehm M, Huber HJ, Hellwig CT, Anguissola S, Dussmann H, Prehn JH. Dynamics of outer mitochondrial membrane permeabilization during apoptosis.  Cell Death Differ. 2009 Apr;16(4):613-23. Epub 2009 Jan 9. PMID: 19136937
• Farrelly AM, Wobser H, Bonner C, Anguissola S, Rehm M, Concannon CG, Prehn JH, Byrne MM. Early loss of mammalian target of rapamycin complex 1 (mTORC1) signalling and reduction in cell size during dominant-negative suppression of hepatic nuclear factor 1-alpha (HNF1A) function in INS-1 insulinoma cells. Diabetologia. 2009 Jan;52(1):136-44. Epub 2008 Oct 24. PMID: 18949455
• Huber HJ, Plchut M, Weisová P, Düssmann H, Wenus J, Rehm M, Ward MW, Prehn JH. TOXI-SIM-A simulation tool for the analysis of mitochondrial and plasma membrane potentials.. J Neurosci Methods. 2009 Jan 30;176(2):270-5. Epub 2008 Sep 7. PMID: 18824028

2008:

• Rudy A, López-Antón N, Barth N, Pettit GR, Dirsch VM, Schulze-Osthoff K, Rehm M, Prehn JH, Vogler M, Fulda S, Vollmar AM. Role of Smac in cephalostatin-induced cell death. Cell Death Differ. 2008 Dec;15(12):1930-40. Epub 2008 Sep 19. PMID: 18806754
• Hetschko H, Voss V, Senft C, Seifert V, Prehn JH, Kögel D. BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells. Neoplasia. 2008 Aug;10(8):873-85. PMID:18670645
• O’Connor CL, Anguissola S, Huber HJ, Dussmann H, Prehn JH, Rehm M. Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein. Biochim Biophys Acta. 2008 Oct;1783(10):1903-13. Epub 2008 Jun 11. PMID:18590777
• Hector S, Tummala R,KisielND, Diegelman P, Vijcic S, Clark K, Fakih M, Kramer DL, Porter CW, Pendyala L. Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine. Cancer Chemotherapy Pharmacology 2008 Aug;62(3):517-27. Epub 2007 Nov 7., PMID: 17987291.
• Köhler B, Anguissola S, Concannon CG, Rehm M, Kögel D, Prehn JH. Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands’ apoptotic and synergistic effects.. PLoS One. 2008 Jul 30;3(7):e2844. PMID: 18665234
• Hellwig CT, Kohler BF, Lehtivarjo AK, Dussmann H, Courtney MJ, Prehn JH, Rehm M. Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation.J Biol Chem. 2008 Aug 1;283(31):21676-85. Epub 2008 Jun 3. PMID: 18522940
• Hetschko H, Voss V, Seifert V, Prehn JH, Kögel D. Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis. FEBS J. 2008 Apr;275(8):1925-36. Epub 2008 Mar 13. PMID: 18341587
• Zuse A, Prinz H, Müller K, Schmidt P, Günther EG, Schweizer F, Prehn JH, Los M. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity.Eur J Pharmacol. 2007 Dec 1;575(1-3):34-45. Epub 2007 Aug 1. PMID: 17707367

2007:

• Huber HJ, Rehm M, Plchut M, Düssmann H, Prehn JH. APOPTO-CELL–a simulation tool and interactive database for analyzing cellular susceptibility to apoptosis. Bioinformatics. 2007 Mar 1;23(5):648-50. Epub 2007 Jan 19. PMID:17237051
• Concannon CG, Koehler BF, Reimertz C, Murphy BM, Bonner C, Thurow N, Ward MW, Villunger A, Strasser A, Kögel D, Prehn JH. Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway. Oncogene. 2007 Mar 15;26(12):1681-92. Epub 2006 Sep 18. PMID:16983338

2006:

• Rehm M, Huber HJ, Dussmann H, Prehn JH. Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. EMBO J. 2006 Sep 20;25(18):4338-49. Epub 2006 Aug 24. PMID: 16932741
• Wobser H, Bonner C, Nolan JJ, Byrne MM, Prehn JH. Downregulation of protein kinase B/Akt-1 mediates INS-1 insulinoma cell apoptosis induced by dominant-negative suppression of hepatocyte nuclear factor-1alpha function. Diabetologia. 2006 Mar;49(3):519-26. Epub 2006 Jan 27. PMID:16440211

2005:

• McDonnell SO, Hall MJ, Allen LT, Byrne A, Gallagher WM, O’Shea DF. Supramolecular photonic therapeutic agents. J Am Chem Soc. 2005 Nov 30;127(47):16360-1  PMID: 16305199.

2003:

• Byrne AT, Ross L, Holash J, Nakanishi M, Hu L, Hofmann JI, Yancopoulos GD, . Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model. Clin Cancer Res. 2003 Nov 15;9(15):5721-8. PMID: 14654557
• Rehm M, Düssmann H, Prehn JH. Real-time single cell analysis of Smac/DIABLO release during apoptosis. J Cell Biol. 2003 Sep 15;162(6):1031-43. PMID:12975347
• Düssmann H, Kögel D, Rehm M, Prehn JH. Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis. J Biol Chem. 2003 Apr 11;278(15):12645-9. Epub 2003 Jan 30. PMID: 12560329
• Düssmann H, Rehm M, Kögel D, Prehn JH. Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis. J Cell Sci. 2003 Feb 1;116(Pt 3):525-36. PMID: 12508113
• Kögel D, Reimertz C, Düssmann H, Mech P, Scheidtmann KH, Prehn JH. The death associated protein (DAP) kinase homologue Dlk/ZIP kinase induces p19ARF- and p53-independent apoptosis. Eur J Cancer. 2003 Jan;39(2):249-56. Erratum in: Eur J Cancer. 2003 Jul;39(10):1466-8. PMID: 12509958
• Byrne AT, Southgate J, Brison DR, Leese HJ .Effects of insulin-like growth factors I and II on tumour-necrosis-factor-alpha-induced apoptosis in early murine embryos  Reprod Fertil Dev. 2002;14(1-2):79-83  PMID: 12051527 (Dec 2002)

2002 and Earlier:

• Byrne AT,SouthgateJ,Brison DR, Leese HJ. Regulation of apoptosis in the bovine blastocyst by insulin and the insulin-like growth factor (IGF) superfamily. Mol Reprod Dev. 2002 Aug;62(4):489-95.     PMID: 12112582      (Aug 2002)
• Rehm M, Dussmann H, Janicke RU, Tavare JM, Kogel D, Prehn JH. Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3. J Biol Chem. 2002 Jul 5;277(27):24506-14. Epub 2002 Apr 18. PMID: 11964393
• Wobser H, Düssmann H, Kögel D, Wang H, Reimertz C, Wollheim CB, Byrne MM, Prehn JH. Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. J Biol Chem. 2002 Feb 22;277(8):6413-21. Epub 2001 Nov 27. PMID:11724785