Professor Jochen Prehn’s research was a focus on the Sunday Times issue 19-2-17 where he talks about how a molecular test developed at the Royal College of Surgeons in Ireland (RCSI) can predict how bowel cancer will respond to chemotherapy, ensuring that patients for whom the procedure is potentially counterproductive do not need to get the treatment.
BowelScreen, a public screening programme, can help to diagnose bowel cancers earlier than before, according to Jochen Prehn, professor of physiology and medical physics at the RCSI, who led the research team.
The test was developed when RCSI gained access to cancer tissue from 400 patients who were part of two large studies in Ireland, Europe and America of people with bowel cancer.
Tuesday 7th February 2017: 17 transition year students from schools across Dublin are taking part in a three day interactive RCSI (Royal College of Surgeons in Ireland) Mini-Science programme, which is running from 6th – 8th February. As part of the course, students will experience life as a scientific researcher. This programme is being co-ordinated by Dr Helena Bonner in the Department of Physiology and Medical Physics at RCSI, in conjunction with the Centre for Systems Medicine, based at RCSI.
An R package developed for handling naming challenges of mature miRNAs. miRNAmeConverter delivers results in a fast and transparent way. Its main functions are to check for validity of mature miRNA names, to determine the most likely miRBase version of a given set of miRNAs and to translate mature miRNA names to different versions (including sequences). A web interface enables users less familiar with R to translate miRNA names given in form of a list or embedded in text and download of the results.
…an easy way to translate mature miRNA names to different versions.If you make use of the miRNAmeConverter please cite:
Haunsberger SJ, Connolly NMC and Prehn JHM* (2016). “miRNAmeConverter: an R/Bioconductor package for translating mature miRNA names to different miRBase versions.” Bioinformatics. doi: 10.1093/bioinformatics/btw660
WORKSHOP “QUANTITATIVE BIOPHOTONICS FOR TRANSLATIONAL SYSTEMS BIOLOGY”
JANUARY 19, 2017 – JANUARY 20, 2017
The workshop will cover principles of quantitative biophotonics applications and how these can be linked to mathematical models as part of translational systems biological strategies.
Lectures are open, all welcome but places are limited!
More information here.
Congratulations to Dr. Triona Ni Chonghaile in receiving an award from the Breast Cancer Now for her two year project entitled ‘Determining the role of the epigenetic reader bromodomain protein 3 in invasive lobular carcinoma’
Dr. Kate Connor is a Postdoctoral Researcher in the RCSI Laboratory for Tumour Biology and Molecular Imaging directed by Dr. Annette Byrne (Senior Lecturer), in the Department of Physiology and Medical Physics. Dr. Connor is funded under an SFI Technology Innovation Development Award (TIDA) with the goal of the project to develop a novel therapies for a form of incurable brain cancer (glioblastoma).
Part of the TIDA award requires researchers to participate in the SFI/EI ‘Get Started Technology Venture Programme’ held at the esteemed DCU Ryan Academy of Entrepreneurship. This program aims to highlight the feasibility of an innovative idea for further commercial exploitation and develops awareness of entrepreneurship and the commercialisation process for researchers in the early stages of the commercialisation pipeline.
The final day of the program took place on Nov 4th with researchers presenting their work to a panel of investors and judges with the aim of highlighting the significant scientific and commercial impact of their research. Winners of this ‘dragons den’ style event have also been given the opportunity to present their pitch at the SFI Summit meeting which took place on Nov 14th in Croke Park.
Dr. Connor was among 4 other successful candidates who were chosen to present their winning pitches at the Summit next week. This event was a wonderful opportunity to showcase the project and to potentially gain investment for future work towards translation of new therapies to brain cancer patients.
Dr. Connor successfully won the popular vote of which presentation deserved further investment.
Dr. Zaitun Zakaria on getting her PhD
and to Dr. Karen Coughlan and Dr. Shona Pfeiffer on obtaining their Diploma in Health Sciences Education
Dr. Sinead Kinsella and Prof. Jochen Prehn published a preview entitled ‘In the Middle of a Chain Interaction’ in the Journal of Molecular Cell-
see below for the link